Just 5% of U.S. farms account for 54% of its beef and dairy cattle, swine, and poultry, concentrating manure as well as animals. These industrial-scale operations, called CAFOs (concentrated animal feeding operations) or factory farms, produce 575 billion pounds of manure yearly. Manure concentration contributes to air and water pollution, and likely to antibiotic resistance, impacting both workers and neighbors. This factsheet outlines the health risks from air pollution caused by CAFOs.